Semaglutide was given the go-ahead by the US Food and Drug Administration (FDA) in 2021 for use in the treatment of obesity. It has long been used as a type 2 diabetic medication.
The hormone (GLP-1) that the human body naturally produces in the small intestine and controls hunger and food intake is imitated by semaglutide.
Moreover, it aids in bettering blood sugar metabolism. Apparently, semaglutide functions very similarly to Saxenda, a popular medication for weight loss.
Is semaglutide a successful weight-loss medication?
Yes. According to studies, Semaglutide can aid in weight loss by suppressing your appetite. Semaglutide aids in the balancing of central hormones to reduce appetite, just as it does with other treatments for obesity like the intragastric balloon.
Keeping insulin levels in check also benefits. The ability to lessen cravings and overeating, which can result in obesity, is also connected to this aspect.
Semaglutide provides a
- Better control over satiety
- A diminished sense of hunger
- Reduction in blood sugar levels
How much weight does semaglutide cause you to lose?
The answer is always the same for any weight-loss procedure: It will depend on each patient and how they adhere to the guidelines given by the medical staff. Studies indicate that they lose between 15% and 20% of their body weight, though.
Who can handle it?
Currently, only patients with a BMI of 30 or higher are eligible. Those with diseases linked to obesity, however, need only have a BMI of 27 to qualify.
It’s also vital to keep in mind that this medication is only appropriate for overweight patients who are willing to adhere to a medically supported treatment plan.
Is semaglutide by itself sufficient for weight loss?
Semaglutide aids in weight loss, but as with any other method of treating obesity, the effectiveness of the treatment is only realized after a sustained change in eating patterns and lifestyle.
In order for the treatment to be more successful and for its benefits to remain longer, it is crucial that it be combined with:
- Medical supervision: Medical supervision will guarantee that the entire procedure is carried out correctly.
- Nutritional advice: It’s difficult to change one’s eating habits. With the right nutritional and dietary guidance, it will be possible to both solidify new eating habits while maximizing the effectiveness of liraglutide.
- Sports advice: To maximize the effects of this new medication, physical exercise is advised together with the indications for use.
- Psychological counseling: The patient may occasionally require psychological counseling to assist him in changing certain attitudes that may have contributed to his unhealthy behaviors and weight gain.
Semaglutide Adverse Reactions
The gastrointestinal side effects of GLP-1 receptor agonist treatment are the most typical.
Exendin-4 derivative-induced immunogenicity, injection site sensitivity responses, nausea, vomiting, and diarrhea. But these incidents are rarely severe or long-lasting (2).
Similar to other anti-diabetic medications, there are some concerns concerning elevated pancreatic lipase and pancreatitis. Patients with a history of chronic or idiopathic acute pancreatitis should not receive treatment with GLP-1 receptor agonists.
Additional contraindications include a family or personal history of multiple endocrine neoplasia type 2, renal insufficiency, or medullary thyroid carcinoma (1). (1).
What happens after receiving semaglutide treatment?
In order to respond to this query, we must first evaluate the outcomes of the placebo group.
If we closely examine any of the trials, we may also see that the placebo group’s body weight declines as well, albeit at a much lower rate.
Each of the four graphs displays the percentage of participants that lose 5, 10, 15, and 20% of their body weight.
In graph D (STEP 4), we can observe that up to 5% of placebo participants experience weight loss of up to 20% over the course of 68 weeks.
Not to mention, both groupsthose receiving semaglutide medication and those receiving a placebounderwent extremely stringent calorie restriction (-500 kcal/day), along with advice to enhance physical exercise. You can easily find Semaglutide for sale online.